Genesis 42:36 And Jacob their father said unto them, Me have ye bereaved of my children: Joseph is not, and Simeon is not, and ye will take Benjamin away: all these things are against me.
Jacob has lost so much. He is focused on what he had and no longer has. Joseph was gone, then Simeon left, and now they wanted to take Benjamin away. The problem is that Jacob is not trusting God in his circumstances. God was actually at work, but it is hard to see above where you are and see what God is doing. Instead of trusting God we tend to focus on what we are losing. Me and my stuff is what I tend to focus on.
Examine yourself right now. Are you focus on your stuff or on Him? Are you focused on what God is doing or on what you are losing? Life is losing. The older we get, the more friends we lose as they die. Our material goods wear out. Our bodies wear out. It is so easy to think that things are bad when you focus on the temporary instead of the eternal.