Jeremiah 25:7 Yet ye have not hearkened unto me, saith the LORD; that ye might provoke me to anger with the works of your hands to your own hurt.
God says that they have not listened. They will not pay attention. They will not take to heart what He has to say to them through His men. They are provoking Him to anger. They do with their own hands. They are bringing their own hurt on themselves.
Why would they choose to on purpose disobey God? Why would they choose to do things that they know angers God? He is warning them. They are refusing to believe Him and to obey Him. Now they will suffer the consequences.