Lamentations 4:16 The anger of the LORD hath divided them; he will no more regard them: They respected not the persons of the priests, they favoured not the elders.
They sinned against God. They angered Him. He had been so good to them. He had met their needs. The people showed no respect to the men of God. They cared not for the Word of God. Now God has divided them. He is not listening to them.
Did you ever think that if you do your own thing too much you cut yourself off from His blessings? Is that really what you want to do?